PCBP4

Across TCGA patient cohorts, PCBP4 mutation is significantly associated with the RNA expression of many other genes, with 2,548 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCBP4-associated genes across cancer lineages are RNU6-855P, SALL4P1, and OR2G2. Each is linked with PCBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCBP4-to-partner and partner-to-PCBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-855P grouped by PCBP4-low versus PCBP4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP4→partner) and Y-score (partner→PCBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-855P →	+0.243	+4.314	<.001	.009	3	2
BLCA	SALL4P1 →	+0.018	+4.433	.004	.007	3	2
COAD	OR2G2 →	+0.088	+6.003	<.001	.002	3	2
UCEC	RRM2P2 →	+0.205	+2.211	.007	.003	3	2
UCEC	RNU6-1294P →	+0.314	+2.375	.002	.005	3	2
BLCA	MIR4727 →	+0.401	+4.314	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,548 associations by consensus.

RNU6-855P by PCBP4 expression — BLCA

Explore this box plot interactively →