PCBP4

Across TCGA cell cohorts, PCBP4 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCBP4-associated genes across cancer lineages are GFRA4, CCR8, and NKX2-6. Each is linked with PCBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCBP4-to-partner and partner-to-PCBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by PCBP4-low versus PCBP4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP4→partner) and Y-score (partner→PCBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GFRA4 →	+0.019	+3.345	.001	.007	3	2
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	GUCY2F →	+0.008	+3.688	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

GFRA4 by PCBP4 expression — LARGE_INTESTINE

Explore this box plot interactively →