PCBP3-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PCBP3-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PCBP3-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PCBP3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PCBP3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and KIRP show a favorable association.

UCEC, UVM, and KIRP are the cancer types where PCBP3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSQuartileAll0.8550.922.00156view →
UVMOSQuartileAll1.0000.698.00342view →
KIRPDFSMedianII,III,IV1.0000.473.00139view →
LIHCDFSTertileAll0.2920.452.00239view →
KIRCDFSQuartileAll0.5020.728.00139view →
COADOSTertileAll0.7970.532.01338view →
READOSTertileII,III,IV1.0000.877.01136view →
DLBCOSMedianAll1.0000.583.00726view →
THYMDFSMedianII,III,IV1.0000.747.00620view →
ACCDFSTertileII,III,IV0.2530.613.01719view →
STADDFSMedianAll0.5020.596.02215view →
ESCADFSMedianAll0.4950.919.01012view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration