Across TCGA pan-cancer cohorts, PCBP3-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of PCBP3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PCBP3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PCBP3-AS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, THCA, and UCEC are the cancer types where PCBP3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PCBP3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.111	<.001	9	view →
THCA	Female	All	+0.027	.013	4	view →
UCEC	All	All	−0.197	.012	2	view →
KIRP	All	All	+0.110	.010	2	view →
BRCA	All	III,IV	−0.024	.014	2	view →
COAD	Female	All	−0.021	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: PCBP3-AS1 RNA expression & survival · all PCBP3-AS1 data types