PBX4

Across TCGA patient cohorts, PBX4 RNA expression is significantly associated with the RNA expression of many other genes, with 17,293 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible PBX4-associated genes across cancer lineages are LPAR2, DCAF15, and RAD9A. Each is linked with PBX4 in more than 32 cancer types. Because this analysis shows association rather than direction, both PBX4-to-partner and partner-to-PBX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PBX4 versus LPAR2 in LIHC, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX4→partner) and Y-score (partner→PBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LPAR2 →	+1.264	+0.488	<.001	<.001	3	33
ACC	DCAF15 →	+0.777	+0.544	<.001	<.001	3	30
ACC	RAD9A →	+0.998	+0.739	<.001	<.001	3	30
KIRP	CCDC130 →	+0.902	+1.031	<.001	<.001	3	30
TGCT	ATAD3B →	+1.045	+0.745	<.001	<.001	3	29
ACC	ARHGAP33 →	+1.314	+0.803	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,293 associations by consensus.

PBX4 vs LPAR2 — LIHC

Explore this scatter interactively →