Across TCGA patient cohorts, PBX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,397 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PBX2-associated proteins across cancer lineages are CMTR1, RXRB, and GNL1. Each is linked with PBX2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PBX2-to-partner and partner-to-PBX2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX2→partner) and Y-score (partner→PBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CMTR1 →	+0.329	+0.573	<.001	<.001	3	7
OV	RXRB →	+0.401	+0.877	<.001	<.001	3	6
LSCC	GNL1 →	+0.225	+0.415	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.315	+0.303	<.001	.001	3	5
OV	XPO5 →	+0.570	+0.741	.001	<.001	3	5
LSCC	ZNF318 →	+0.292	+0.291	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,397 associations by consensus.

Exploration

PBX2 survival (RNA) · tumor vs normal (RNA) · all PBX2 data types