Across TCGA patient cohorts, PBX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PBX1-associated proteins across cancer lineages are RPL7, UNC13D, and RCOR3. Each is linked with PBX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PBX1-to-partner and partner-to-PBX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX1→partner) and Y-score (partner→PBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.419	-0.593	<.001	<.001	3	7
UCEC	UNC13D →	-0.462	-0.781	.001	.003	3	7
BRCA	RCOR3 →	+0.411	+1.328	<.001	<.001	3	7
BRCA	RO60 →	+0.322	+1.161	<.001	<.001	3	7
BRCA	ERO1A →	-0.738	-1.030	<.001	<.001	3	7
CCRCC	RPL5 →	-0.276	-1.146	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,849 associations by consensus.

Exploration

PBX1 survival (RNA) · tumor vs normal (RNA) · all PBX1 data types