Across TCGA patient cohorts, PBX1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,517 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PBX1-associated genes across cancer lineages are FXYD6, MEIS1, and BOC. Each is linked with PBX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PBX1-to-partner and partner-to-PBX1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PBX1→partner) and Y-score (partner→PBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FXYD6 →	+1.358	+0.594	<.001	<.001	3	7
OV	MEIS1 →	+1.252	+0.467	<.001	<.001	3	7
LSCC	BOC →	+1.079	+0.437	<.001	<.001	3	7
COAD	MFAP4 →	+1.297	+0.441	<.001	<.001	3	7
COAD	C7 →	+1.946	+0.382	<.001	<.001	3	6
CCRCC	COL14A1 →	+1.401	+0.762	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,517 associations by consensus.

Exploration

PBX1 survival (RNA) · tumor vs normal (RNA) · all PBX1 data types