PAX1

Across TCGA patient cohorts, PAX1 protein abundance is significantly associated with the RNA expression of many other genes, with 387 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PAX1-associated genes across cancer lineages are ASIC2, TPO, and MCCC2. Each is linked with PAX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAX1-to-partner and partner-to-PAX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAX1 versus ASIC2 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX1→partner) and Y-score (partner→PAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASIC2 →	+1.532	+0.398	.001	<.001	3	1
UCEC	TPO →	+1.123	+0.485	.007	.002	3	1
UCEC	MCCC2 →	-1.602	-0.531	<.001	.002	3	1
UCEC	SORD →	-1.909	-0.441	.004	.008	3	1
UCEC	CABYR →	-1.574	-0.372	.001	.002	3	1
UCEC	CYLC2 →	+0.223	+0.378	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 387 associations by consensus.

PAX1 vs ASIC2 — UCEC

Explore this scatter interactively →