PAX1

Across TCGA cell cohorts, PAX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 722 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PAX1-associated GO terms across cancer lineages are Visual perception, Sensory perception of light stimulus, and Diencephalon development. Each is linked with PAX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAX1-to-partner and partner-to-PAX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Visual perception grouped by PAX1-low versus PAX1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAX1→partner) and Y-score (partner→PAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Visual perception →	-0.056	-0.883	.001	.001	3	4
LUNG_NSCLC_LUSC	Sensory perception of light stimulus →	-0.041	-0.037	.003	.006	3	4
LUNG_NSCLC_LUAD	Diencephalon development →	-0.129	-0.144	<.001	.004	3	3
OVARY	Embryonic organ development →	-0.029	-0.362	.002	.005	2	4
OVARY	Regulation of translational fidelity →	+0.068	+0.205	<.001	.004	3	3
OVARY	Gamma-aminobutyric acid signaling pathway →	-0.270	-0.369	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 722 associations by consensus.

Visual perception by PAX1 expression — BONE

Explore this box plot interactively →