PATZ1

Across TCGA pan-cancer cohorts, PATZ1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PATZ1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PATZ1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PATZ1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, GBM, and CCRCC are the cancer types where PATZ1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.927	0.698	<.001	39	view →
GBM	OS	Tertile	All	0.549	0.332	.024	4	view →
CCRCC	OS	Median	IV	1.000	0.451	.032	3	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.902	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PATZ1–LSCC (OS)

Open the LSCC breakdown →