PATZ1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PATZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,698 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PATZ1-associated genes across cancer lineages are COPG2, LRP6, and YPEL1. Each is linked with PATZ1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PATZ1-to-partner and partner-to-PATZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PATZ1 versus COPG2 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PATZ1→partner) and Y-score (partner→PATZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCOPG2 →+0.566+0.414<.001<.00135
HNSCLRP6 →+0.767+0.438.003<.00135
LSCCYPEL1 →+0.792+0.471<.001<.00135
BRCAC14orf93 →+0.520+0.458<.001<.00135
GBMRPAIN →+0.482+0.574<.001<.00135
HNSCPGBD1 →+0.941+0.426<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,698 associations by consensus.

PATZ1 vs COPG2 — LSCC

Per-sample scatter of PATZ1 vs COPG2 in LSCC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration