PATZ1

Across TCGA cell cohorts, PATZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,320 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PATZ1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of DNA repair, and Positive regulation of DNA metabolic process. Each is linked with PATZ1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PATZ1-to-partner and partner-to-PATZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by PATZ1-low versus PATZ1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PATZ1→partner) and Y-score (partner→PATZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.083	+1.221	.001	<.001	3	15
BONE	Positive regulation of DNA repair →	+0.089	+1.309	<.001	<.001	3	14
BONE	Positive regulation of DNA metabolic process →	+0.064	+0.831	<.001	<.001	3	14
BONE	Regulation of DNA repair →	+0.101	+1.261	<.001	<.001	3	13
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.141	+0.681	<.001	<.001	3	13
BONE	Internal peptidyl-lysine acetylation →	+0.235	+1.502	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,320 associations by consensus.

Epigenetic regulation of gene expression by PATZ1 expression — BONE

Explore this box plot interactively →