PATL1

Across TCGA pan-cancer cohorts, PATL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PATL1 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PATL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PATL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where PATL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	1.000	0.903	.004	23	view →
PDAC	OS	Tertile	II,III,IV	0.257	0.477	.013	18	view →
CCRCC	DFS	Quartile	III,IV	0.265	0.798	.006	6	view →
LUAD	DFS	Median	III,IV	0.886	0.595	.014	6	view →
LSCC	DFS	Median	II,III,IV	0.971	0.855	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PATL1–HNSC (DFS)

Open the HNSC breakdown →