PATL1

Across TCGA patient cohorts, PATL1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,883 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PATL1-associated genes across cancer lineages are CENPA, CDCA5, and CHEK1. Each is linked with PATL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PATL1-to-partner and partner-to-PATL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PATL1 versus CENPA in LUAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PATL1→partner) and Y-score (partner→PATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPA →	+1.164	+0.220	<.001	<.001	3	7
LUAD	CDCA5 →	+1.153	+0.227	<.001	<.001	3	7
LUAD	CHEK1 →	+1.093	+0.255	<.001	<.001	3	7
COAD	PLK1 →	+0.835	+0.212	<.001	.003	3	7
LSCC	STIP1 →	+0.653	+0.252	<.001	<.001	3	7
LUAD	FEN1 →	+0.829	+0.236	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,883 associations by consensus.

PATL1 vs CENPA — LUAD

Explore this scatter interactively →