PATL1

Across TCGA cell cohorts, PATL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PATL1-associated GO terms across cancer lineages are Regulation of heterochromatin organization, Regulation of anaphase-promoting complex-dependent catabolic process, and Mitotic spindle elongation. Each is linked with PATL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PATL1-to-partner and partner-to-PATL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heterochromatin organization grouped by PATL1-low versus PATL1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PATL1→partner) and Y-score (partner→PATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of heterochromatin organization →	+0.105	+0.823	<.001	<.001	3	13
LUNG_SCLC	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.153	+0.705	<.001	<.001	3	12
BLOOD_Lymphoma	Mitotic spindle elongation →	+0.177	+0.905	<.001	<.001	3	12
BLOOD_Lymphoma	Mitotic spindle midzone assembly →	+0.177	+0.905	<.001	<.001	3	12
BREAST	Negative regulation of cell cycle process →	+0.055	+0.892	<.001	<.001	3	11
SOFT_TISSUE	Protein deubiquitination →	+0.043	+0.568	.005	.006	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,697 associations by consensus.

Regulation of heterochromatin organization by PATL1 expression — URINARY_TRACT

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