PATJ

Across TCGA cell cohorts, PATJ mutation is significantly associated with the RNA expression of many other genes, with 351 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PATJ-associated genes across cancer lineages are C3orf52, ID2, and KDSR. Each is linked with PATJ in more than 1 cancer types. Because this analysis shows association rather than direction, both PATJ-to-partner and partner-to-PATJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C3orf52 grouped by PATJ-low versus PATJ-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PATJ→partner) and Y-score (partner→PATJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C3orf52 →	-0.677	-3.416	.009	.002	3	2
LARGE_INTESTINE	ID2 →	+1.240	+3.502	.005	.001	3	2
LARGE_INTESTINE	KDSR →	+0.697	+3.502	.003	.001	3	2
LARGE_INTESTINE	ZCCHC4 →	+0.511	+3.169	<.001	.009	3	2
LARGE_INTESTINE	STX8 →	+0.530	+2.537	.005	.008	3	2
LARGE_INTESTINE	ELMOD2 →	+0.498	+3.169	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

C3orf52 by PATJ expression — LARGE_INTESTINE

Explore this box plot interactively →