PATE4

Across TCGA cell cohorts, PATE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,652 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PATE4-associated GO terms across cancer lineages are Regulation of protein K48-linked ubiquitination, Regulation of mitotic sister chromatid segregation, and Regulation of chromosome organization. Each is linked with PATE4 in more than 6 cancer types. Because this analysis shows association rather than direction, both PATE4-to-partner and partner-to-PATE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K48-linked ubiquitination grouped by PATE4-low versus PATE4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PATE4→partner) and Y-score (partner→PATE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein K48-linked ubiquitination →	+0.094	+0.055	.002	.001	3	7
BLOOD_Leukemia	Regulation of mitotic sister chromatid segregation →	+0.050	+0.048	.006	.003	3	7
BREAST	Regulation of chromosome organization →	+0.072	+0.107	<.001	.002	3	6
SKIN	Microtubule organizing center organization →	+0.045	+0.062	<.001	<.001	3	6
SKIN	Signal transduction in response to DNA damage →	+0.036	+0.081	.001	<.001	3	6
BLOOD_Leukemia	Regulation of nuclear division →	+0.046	+0.052	.008	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,652 associations by consensus.

Regulation of protein K48-linked ubiquitination by PATE4 expression — STOMACH

Explore this box plot interactively →