PATE4

Across TCGA pan-cancer cohorts, PATE4 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PATE4 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher PATE4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PATE4 expression acts as an unfavorable survival marker, although some lineages such as LAML and SCLC show a favorable association.

TGCT, KIRP, and LAML are the cancer types where PATE4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	II,III,IV	0.421	0.996	<.001	84	view →
KIRP	DFS	Quartile	III,IV	0.123	0.538	.001	30	view →
LAML	DFS	Quartile	All	0.779	0.431	.013	28	view →
SCLC	DFS	Tertile	II,III,IV	0.512	0.211	.019	27	view →
GBM	OS	Tertile	All	0.329	0.234	.012	23	view →
CESC	DFS	Tertile	II,III,IV	0.625	0.845	<.001	22	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	21	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
BLCA	OS	Median	IV	0.373	0.203	.011	13	view →
PAAD	OS	Quartile	All	0.639	0.412	.025	9	view →
MESO	DFS	Tertile	IV	0.079	0.414	.004	9	view →
BRCA	DFS	Tertile	All	0.972	0.934	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PATE4–TGCT (DFS)

Open the TGCT breakdown →