PATE3

Across TCGA pan-cancer cohorts, PATE3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated PATE3 data layer compared with 2 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher PATE3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PATE3 expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

UVM, LIHC, and ACC are the cancer types where PATE3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
LIHC	OS	Tertile	II,III,IV	0.072	0.702	<.001	51	view →
ACC	DFS	Tertile	All	0.166	0.579	.035	27	view →
CESC	OS	Tertile	III,IV	0.460	0.776	.026	24	view →
PAAD	OS	Tertile	All	0.884	0.454	.029	18	view →
LGG	DFS	Tertile	All	0.241	0.444	.008	18	view →
LUSC	OS	Tertile	III,IV	0.182	0.794	.002	18	view →
STAD	DFS	Quartile	IV	0.146	0.469	.018	15	view →
HNSC	OS	Tertile	III,IV	0.279	0.558	.028	12	view →
PCPG	DFS	Tertile	All	0.639	0.875	.031	9	view →
OV	OS	Median	III,IV	0.873	0.799	.029	4	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

PATE3–UVM (OS)

Open the UVM breakdown →