PATE3

Across TCGA pan-cancer cohorts, PATE3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PATE3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PATE3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PATE3 is over-expressed in tumor, although a few such as PRAD and KIRC show the opposite, repressed pattern.

HNSC, PRAD, and BRCA are the cancer types where PATE3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PATE3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.030	.028	4	view →
PRAD	All	All	−0.593	.006	2	view →
BRCA	Female	All	+0.036	.048	2	view →
KIRC	All	III,IV	−0.007	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

PATE3–HNSC

Open the HNSC breakdown →