PATE1

Across TCGA cell cohorts, PATE1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PATE1-associated genes across cancer lineages are PRSS58. Each is linked with PATE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PATE1-to-partner and partner-to-PATE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by PATE1-low versus PATE1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PATE1→partner) and Y-score (partner→PATE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PRSS58 by PATE1 expression — PANCREAS

Explore this box plot interactively →