PATE1

Across TCGA pan-cancer cohorts, PATE1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PATE1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PATE1 RNA is repressed in tumor relative to normal tissue. In most cancer types PATE1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and KICH are the cancer types where PATE1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PATE1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	−0.097	<.001	11	view →
KIRP	All	All	−0.047	<.001	5	view →
KICH	Male	II,III,IV	−0.051	.028	3	view →
PRAD	All	All	−1.744	<.001	2	view →
THCA	Female	All	−0.010	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PATE1–KIRC

Open the KIRC breakdown →