Across TCGA cell cohorts, PARVB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,171 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PARVB-associated GO terms across cancer lineages are Establishment or maintenance of cell polarity regulating cell shape, Carbohydrate biosynthetic process, and Hexose biosynthetic process. Each is linked with PARVB in more than 13 cancer types. Because this analysis shows association rather than direction, both PARVB-to-partner and partner-to-PARVB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVB→partner) and Y-score (partner→PARVB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment or maintenance of cell polarity regulating cell shape →	+0.188	+2.207	<.001	<.001	3	14
SKIN	Carbohydrate biosynthetic process →	+0.086	+1.769	<.001	.003	3	9
SKIN	Hexose biosynthetic process →	+0.143	+2.062	<.001	<.001	3	8
LUNG_SCLC	GTP biosynthetic process →	+0.128	+1.478	<.001	<.001	3	8
BONE	Protein folding →	+0.074	+3.236	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Ribonucleotide metabolic process →	+0.047	+2.167	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,171 associations by consensus.

Exploration

PARVB survival (RNA) · tumor vs normal (RNA) · all PARVB data types