Across TCGA patient cohorts, PARPBP RNA expression is significantly associated with the protein abundance of many other proteins, with 28,030 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARPBP-associated proteins across cancer lineages are CDC20_T70, CDK1, and CHAF1A_S141. Each is linked with PARPBP in more than 9 cancer types. Because this analysis shows association rather than direction, both PARPBP-to-partner and partner-to-PARPBP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARPBP→partner) and Y-score (partner→PARPBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC20_T70 →	+1.446	+0.964	<.001	<.001	3	10
LUAD	CDK1 →	+0.986	+0.972	<.001	<.001	3	10
LSCC	CHAF1A_S141 →	+0.904	+0.941	<.001	<.001	3	10
LUAD	ECT2_T359 →	+1.698	+1.047	<.001	<.001	3	10
LSCC	RIF1 →	+0.541	+0.987	<.001	<.001	3	10
LUAD	RRM2 →	+0.959	+0.927	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,030 associations by consensus.

Exploration

PARPBP survival (RNA) · tumor vs normal (RNA) · all PARPBP data types