Across TCGA cell cohorts, PARPBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,469 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PARPBP-associated GO terms across cancer lineages are Regulation of cell cycle G2/M phase transition, Mitotic sister chromatid segregation, and Double-strand break repair via homologous recombination. Each is linked with PARPBP in more than 19 cancer types. Because this analysis shows association rather than direction, both PARPBP-to-partner and partner-to-PARPBP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARPBP→partner) and Y-score (partner→PARPBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of cell cycle G2/M phase transition →	+0.087	+1.010	.001	.001	3	20
SKIN	Mitotic sister chromatid segregation →	+0.136	+1.034	<.001	<.001	3	19
BONE	Double-strand break repair via homologous recombination →	+0.109	+0.972	.002	.004	3	19
BONE	Recombinational repair →	+0.110	+1.007	.002	.003	3	19
BREAST	Positive regulation of cell cycle process →	+0.095	+0.798	<.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.074	+1.149	.005	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,469 associations by consensus.

Exploration

PARPBP survival (RNA) · tumor vs normal (RNA) · all PARPBP data types