PARP4P1

Across TCGA patient cohorts, PARP4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,976 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PARP4P1-associated GO terms across cancer lineages are Autophagosome organization, mRNA alternative polyadenylation, and Regulation of vacuole organization. Each is linked with PARP4P1 in more than 20 cancer types. Because this analysis shows association rather than direction, both PARP4P1-to-partner and partner-to-PARP4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by PARP4P1-low versus PARP4P1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP4P1→partner) and Y-score (partner→PARP4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Autophagosome organization →	+0.033	+0.195	.002	.003	2	21
UVM	mRNA alternative polyadenylation →	+0.063	+0.266	<.001	<.001	3	19
THYM	Regulation of vacuole organization →	+0.033	+0.187	.005	<.001	3	19
UVM	Post-Golgi vesicle-mediated transport →	+0.047	+0.261	<.001	<.001	3	19
UCS	COPII-coated vesicle cargo loading →	+0.110	+0.356	<.001	<.001	3	19
UVM	Vesicle tethering →	+0.041	+0.163	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,976 associations by consensus.

Autophagosome organization by PARP4P1 expression — UCS

Explore this box plot interactively →