PARP2

Across TCGA patient cohorts, PARP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,555 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PARP2-associated proteins across cancer lineages are SSRP1, SUPT16H, and MCM4. Each is linked with PARP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PARP2-to-partner and partner-to-PARP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP2 versus SSRP1 in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP2→partner) and Y-score (partner→PARP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SSRP1 →	+0.504	+0.540	<.001	<.001	3	10
GBM	SUPT16H →	+0.499	+0.562	<.001	<.001	3	10
GBM	MCM4 →	+0.579	+0.374	<.001	.004	3	9
GBM	MTA1 →	+0.517	+0.590	<.001	<.001	3	8
LSCC	MTA1_S576 →	+0.658	+0.482	<.001	<.001	3	8
OV	MTHFD1 →	+0.367	+0.701	.004	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,555 associations by consensus.

PARP2 vs SSRP1 — GBM

Explore this scatter interactively →