PARP14

Across TCGA patient cohorts, PARP14 protein abundance is significantly associated with the RNA expression of many other genes, with 15,122 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PARP14-associated genes across cancer lineages are ETV7, SAMHD1, and LILRB1. Each is linked with PARP14 in more than 9 cancer types. Because this analysis shows association rather than direction, both PARP14-to-partner and partner-to-PARP14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP14 versus ETV7 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP14→partner) and Y-score (partner→PARP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.351	+0.500	<.001	<.001	3	10
HNSC	SAMHD1 →	+0.761	+0.383	<.001	<.001	3	10
GBM	LILRB1 →	+0.723	+0.297	<.001	<.001	3	10
BRCA	DDX58 →	+1.143	+0.411	<.001	<.001	3	10
HNSC	SLC15A3 →	+0.793	+0.393	<.001	<.001	3	10
BRCA	OAS3 →	+1.428	+0.436	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,122 associations by consensus.

PARP14 vs ETV7 — BRCA

Explore this scatter interactively →