PARK7

Across TCGA patient cohorts, PARK7 protein abundance is significantly associated with the RNA expression of many other genes, with 16,844 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PARK7-associated genes across cancer lineages are CBX7, ABCA8, and NCAPH. Each is linked with PARK7 in more than 6 cancer types. Because this analysis shows association rather than direction, both PARK7-to-partner and partner-to-PARK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARK7 versus CBX7 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARK7→partner) and Y-score (partner→PARK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CBX7 →	+0.682	+0.306	<.001	<.001	3	7
HNSC	ABCA8 →	+1.077	+0.272	<.001	<.001	3	7
BRCA	NCAPH →	-0.774	-0.374	<.001	<.001	3	6
LUAD	SCN7A →	+1.278	+0.241	<.001	<.001	3	6
UCEC	TPRG1L →	+0.949	+0.319	<.001	<.001	3	6
GBM	E2F7 →	-0.912	-0.179	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,844 associations by consensus.

PARK7 vs CBX7 — BRCA

Explore this scatter interactively →