PARD6G

Across TCGA patient cohorts, PARD6G protein abundance is significantly associated with the RNA expression of many other genes, with 8,244 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARD6G-associated genes across cancer lineages are LAMA4, MFAP2, and CNRIP1. Each is linked with PARD6G in more than 3 cancer types. Because this analysis shows association rather than direction, both PARD6G-to-partner and partner-to-PARD6G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD6G versus LAMA4 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6G→partner) and Y-score (partner→PARD6G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LAMA4 →	+0.947	+0.404	<.001	<.001	3	4
BRCA	MFAP2 →	+1.034	+0.414	<.001	<.001	3	4
PDAC	CNRIP1 →	+0.658	+0.431	<.001	<.001	3	4
BRCA	CD93 →	+0.683	+0.318	.001	.005	3	4
OV	TSPAN18 →	+1.888	+0.750	.005	.009	3	4
LUAD	NBAT1 →	+1.071	+0.378	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,244 associations by consensus.

PARD6G vs LAMA4 — BRCA

Explore this scatter interactively →