PARD6B

Across TCGA patient cohorts, PARD6B protein abundance is significantly associated with the RNA expression of many other genes, with 11,706 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PARD6B-associated genes across cancer lineages are CGN, OCLN, and SDC4. Each is linked with PARD6B in more than 6 cancer types. Because this analysis shows association rather than direction, both PARD6B-to-partner and partner-to-PARD6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD6B versus CGN in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6B→partner) and Y-score (partner→PARD6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CGN →	+0.971	+0.477	<.001	<.001	3	7
LUAD	OCLN →	+0.975	+0.349	<.001	<.001	3	6
UCEC	SDC4 →	+0.721	+0.378	.002	.002	2	6
COAD	BCL2L1 →	+0.622	+0.391	.002	.001	3	4
HNSC	ARHGAP9 →	-0.863	-0.550	.002	<.001	3	4
HNSC	GAB3 →	-1.037	-0.556	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,706 associations by consensus.

PARD6B vs CGN — BRCA

Explore this scatter interactively →