PARD6B

Across TCGA cell cohorts, PARD6B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,147 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PARD6B-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Establishment of apical/basal cell polarity, and Cellular response to xenobiotic stimulus. Each is linked with PARD6B in more than 13 cancer types. Because this analysis shows association rather than direction, both PARD6B-to-partner and partner-to-PARD6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by PARD6B-low versus PARD6B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6B→partner) and Y-score (partner→PARD6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Establishment of epithelial cell apical/basal polarity →	-0.173	-1.065	.002	.002	3	14
PANCREAS	Establishment of apical/basal cell polarity →	-0.177	-0.983	<.001	.003	3	12
BREAST	Cellular response to xenobiotic stimulus →	-0.094	-1.492	<.001	<.001	3	11
SOFT_TISSUE	Establishment or maintenance of monopolar cell polarity →	-0.109	-1.082	<.001	<.001	3	10
BONE	Regulation of thrombin-activated receptor signaling pathway →	-1.322	-1.470	.001	<.001	3	10
BONE	Negative regulation of thrombin-activated receptor signaling pathway →	-1.322	-1.470	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,147 associations by consensus.

Establishment of epithelial cell apical/basal polarity by PARD6B expression — PANCREAS

Explore this box plot interactively →