PAQR4

Across TCGA patient cohorts, PAQR4 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PAQR4-associated genes across cancer lineages are RNU6-326P, MIR30E, and LINC01706. Each is linked with PAQR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR4-to-partner and partner-to-PAQR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-326P grouped by PAQR4-low versus PAQR4-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR4→partner) and Y-score (partner→PAQR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-326P →	+0.258	+7.939	<.001	.008	3	2
BLCA	MIR30E →	+0.534	+5.588	<.001	.004	3	2
UCEC	LINC01706 →	+0.076	+3.884	<.001	.002	3	2
BRCA	MIR6892 →	+0.323	+6.442	<.001	.001	3	1
BRCA	RN7SL460P →	+0.132	+5.175	.005	.007	3	1
BRCA	RN7SL311P →	+0.141	+5.841	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

RNU6-326P by PAQR4 expression — PRAD

Explore this box plot interactively →