PAQR4

Across TCGA cell cohorts, PAQR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,101 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PAQR4-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Chromosome condensation, and Symbiont-mediated disruption of host cell PML body. Each is linked with PAQR4 in more than 15 cancer types. Because this analysis shows association rather than direction, both PAQR4-to-partner and partner-to-PAQR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by PAQR4-low versus PAQR4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR4→partner) and Y-score (partner→PAQR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication-dependent chromatin assembly →	+0.171	+1.949	<.001	.001	3	16
OESOPHAGUS	Chromosome condensation →	+0.162	+1.087	.006	.004	3	15
OVARY	Symbiont-mediated disruption of host cell PML body →	+0.083	+0.810	<.001	<.001	3	14
BONE	Mitotic DNA replication →	+0.209	+1.474	.006	.001	3	13
BLOOD_Myeloma	DNA-templated DNA replication maintenance of fidelity →	+0.129	+1.633	<.001	.003	3	13
BONE	Cell cycle DNA replication initiation →	+0.182	+1.220	.006	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,101 associations by consensus.

DNA replication-dependent chromatin assembly by PAQR4 expression — BLOOD_Myeloma

Explore this box plot interactively →