PAQR3

Across TCGA patient cohorts, PAQR3 protein abundance is significantly associated with the RNA expression of many other genes, with 726 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PAQR3-associated genes across cancer lineages are COQ2, CLPX, and RSPH6A. Each is linked with PAQR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAQR3-to-partner and partner-to-PAQR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAQR3 versus COQ2 in LUAD, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAQR3→partner) and Y-score (partner→PAQR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	COQ2 →	+0.761	+0.575	<.001	.009	3	2
LUAD	CLPX →	+0.660	+0.505	.002	.006	3	2
BRCA	RSPH6A →	+0.145	+1.006	<.001	.002	3	1
BRCA	MAPK10 →	+1.346	+0.929	.002	.005	3	1
BRCA	WWC1 →	+0.736	+1.053	.006	.004	3	1
BRCA	TNFSF4 →	-1.073	-0.973	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 726 associations by consensus.

PAQR3 vs COQ2 — LUAD

Explore this scatter interactively →