Across TCGA patient cohorts, PAPOLB RNA expression is significantly associated with the protein abundance of many other proteins, with 13,339 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAPOLB-associated proteins across cancer lineages are PTPN11_Y62, HNRNPU, and SARM1. Each is linked with PAPOLB in more than 3 cancer types. Because this analysis shows association rather than direction, both PAPOLB-to-partner and partner-to-PAPOLB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAPOLB→partner) and Y-score (partner→PAPOLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTPN11_Y62 →	+1.325	+0.229	<.001	.002	3	4
LSCC	HNRNPU →	+0.178	+0.198	<.001	<.001	3	4
UCEC	SARM1 →	+0.470	+0.394	<.001	<.001	3	4
CCRCC	PMM2 →	-0.287	-0.093	.001	.006	3	4
CCRCC	HDGFL3 →	+0.364	+0.082	<.001	<.001	3	4
CCRCC	CRMP1 →	+0.660	+0.107	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,339 associations by consensus.

Exploration

PAPOLB survival (RNA) · tumor vs normal (RNA) · all PAPOLB data types