PANK2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PANK2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,051 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PANK2-associated genes across cancer lineages are ZNF791, PRDX3, and TUFM. Each is linked with PANK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PANK2-to-partner and partner-to-PANK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PANK2 versus ZNF791 in OV, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PANK2→partner) and Y-score (partner→PANK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZNF791 →+0.537+0.208.003.00734
LUADPRDX3 →-0.373-0.169<.001<.00133
LUADTUFM →-0.420-0.229<.001<.00133
UCECZNF385D →+0.399+0.148.003.00433
HNSCMS4A1 →+1.045+0.222.007.00933
LUADCLECL1 →+0.729+0.230<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,051 associations by consensus.

PANK2 vs ZNF791 — OV

Per-sample scatter of PANK2 vs ZNF791 in OV (Pearson r = 0.30).

Explore this scatter interactively →

Exploration