PANK1

Across TCGA patient cohorts, PANK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,766 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PANK1-associated proteins across cancer lineages are PPP1R18, CAPZB, and ARPC2. Each is linked with PANK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PANK1-to-partner and partner-to-PANK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PANK1 versus PPP1R18 in UCEC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PANK1→partner) and Y-score (partner→PANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R18 →	-0.440	-0.506	<.001	.002	3	8
GBM	CAPZB →	-0.210	-0.468	<.001	.003	3	7
HNSC	ARPC2 →	-0.358	-0.722	<.001	.001	3	6
GBM	ACTR2 →	-0.171	-0.500	<.001	<.001	3	6
HNSC	ACTR3 →	-0.234	-0.603	<.001	.001	3	6
GBM	CASP4 →	-0.472	-0.498	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,766 associations by consensus.

PANK1 vs PPP1R18 — UCEC

Explore this scatter interactively →