PANDAR

Across TCGA patient cohorts, PANDAR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,428 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PANDAR-associated GO terms across cancer lineages are RIG-I signaling pathway, Negative regulation of innate immune response, and Activation of innate immune response. Each is linked with PANDAR in more than 10 cancer types. Because this analysis shows association rather than direction, both PANDAR-to-partner and partner-to-PANDAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RIG-I signaling pathway grouped by PANDAR-low versus PANDAR-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PANDAR→partner) and Y-score (partner→PANDAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RIG-I signaling pathway →	+0.062	+0.078	<.001	<.001	2	11
UVM	Negative regulation of innate immune response →	+0.047	+0.011	<.001	.009	1	11
ESCA	Activation of innate immune response →	+0.039	+0.053	.004	.001	2	9
ESCA	Tolerance induction →	+0.066	+0.068	.005	<.001	3	8
STAD	Regulation of tolerance induction →	+0.051	+0.072	<.001	<.001	3	8
STAD	Regulation of production of molecular mediator of immune response →	+0.034	+0.062	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,428 associations by consensus.

RIG-I signaling pathway by PANDAR expression — STAD

Explore this box plot interactively →