PANCR

Across TCGA pan-cancer cohorts, PANCR RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of PANCR’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where PANCR RNA is repressed in tumor relative to normal tissue. In most cancer types PANCR is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and HNSC are the cancer types where PANCR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PANCR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−0.250	<.001	11	view →
KICH	Male	II,III,IV	−1.117	<.001	10	view →
HNSC	All	III,IV	−0.803	<.001	10	view →
LUAD	All	All	+0.075	<.001	4	view →
BRCA	All	II,III,IV	+0.014	.020	4	view →
KIRP	All	All	−0.482	.021	3	view →
LUSC	All	All	+0.019	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

PANCR–BLCA

Open the BLCA breakdown →