Q-omics provides the consensus-scored PANCR profile across patient tissues and cancer cell-line models. PANCR expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, PANCR is differentially expressed in 7, with the highest sampling consensus in BLCA. Additionally, PANCR RNA expression shows 9,230 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight CESC, BLCA, and TGCT as cancer lineages where PANCR shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PANCR — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PANCR survival associations across molecular data types. PANCR RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PANCR RNA expression–survival associations across cancer types. High PANCR expression shows unfavorable associations in CESC, MESO, THCA, COAD and LGG, but favorable associations in UCS. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for PANCR RNA expression.
This table summarizes PANCR tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for PANCR. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PANCR shows lower tumor expression in BLCA, KICH, HNSC and KIRP and higher tumor expression in LUAD and BRCA. The BLCA box plot shows higher PANCR RNA expression in normal versus tumor tissue (log2 FC = −0.250, t-test p < 0.001).
This table shows molecular features associated with PANCR in patient tissues and cancer cell lines. In patient samples, PANCR shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
