PAN3

Across TCGA cell cohorts, PAN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,219 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PAN3-associated GO terms across cancer lineages are Positive regulation of cytoplasmic mRNA processing body assembly, Regulation of cytoplasmic mRNA processing body assembly, and RNA destabilization. Each is linked with PAN3 in more than 18 cancer types. Because this analysis shows association rather than direction, both PAN3-to-partner and partner-to-PAN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic mRNA processing body assembly grouped by PAN3-low versus PAN3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAN3→partner) and Y-score (partner→PAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.142	+0.887	<.001	<.001	3	19
LUNG_SCLC	Regulation of cytoplasmic mRNA processing body assembly →	+0.129	+0.776	<.001	<.001	3	18
LUNG_NSCLC_LUSC	RNA destabilization →	+0.081	+0.441	<.001	<.001	3	17
LUNG_NSCLC_LUSC	mRNA destabilization →	+0.084	+0.485	<.001	<.001	3	17
OESOPHAGUS	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.105	+0.640	<.001	.001	3	16
LUNG_NSCLC_LUSC	Regulation of RNA stability →	+0.071	+0.511	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,219 associations by consensus.

Positive regulation of cytoplasmic mRNA processing body assembly by PAN3 expression — SOFT_TISSUE

Explore this box plot interactively →