Across TCGA patient cohorts, PALM3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,532 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PALM3-associated genes across cancer lineages are FOLR1, MISP3, and RGN. Each is linked with PALM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PALM3-to-partner and partner-to-PALM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALM3→partner) and Y-score (partner→PALM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FOLR1 →	+1.877	+0.717	.005	.008	2	5
OV	MISP3 →	+1.005	+0.969	.001	<.001	3	4
CCRCC	RGN →	+1.323	+0.551	<.001	<.001	3	4
LUAD	KCNK5 →	+0.876	+0.461	<.001	<.001	3	4
LSCC	PSMD11 →	-0.689	-0.531	<.001	<.001	3	3
LSCC	RAD23B →	-0.468	-0.407	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,532 associations by consensus.

Exploration

PALM3 survival (RNA) · tumor vs normal (RNA) · all PALM3 data types