PAIP1

Across TCGA patient cohorts, PAIP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,118 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAIP1-associated proteins across cancer lineages are C5orf51, MZB1, and NSUN2. Each is linked with PAIP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PAIP1-to-partner and partner-to-PAIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAIP1 versus C5orf51 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAIP1→partner) and Y-score (partner→PAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C5orf51 →	+0.332	+0.683	<.001	<.001	3	6
BRCA	MZB1 →	-0.709	-0.312	.001	.004	3	5
LSCC	NSUN2 →	+0.374	+0.654	<.001	<.001	3	5
HNSC	HMGB3 →	+0.715	+0.854	<.001	.001	3	5
UCEC	ITPR1 →	-0.413	-0.335	<.001	<.001	3	5
LSCC	WDR70 →	+0.446	+0.729	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,118 associations by consensus.

PAIP1 vs C5orf51 — LSCC

Explore this scatter interactively →