PAICSP6

Across TCGA patient cohorts, PAICSP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,770 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PAICSP6-associated GO terms across cancer lineages are Regulation of double-strand break repair, Positive regulation of ubiquitin-dependent protein catabolic process, and Regulation of cell cycle G2/M phase transition. Each is linked with PAICSP6 in more than 8 cancer types. Because this analysis shows association rather than direction, both PAICSP6-to-partner and partner-to-PAICSP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by PAICSP6-low versus PAICSP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAICSP6→partner) and Y-score (partner→PAICSP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair →	+0.053	+0.031	<.001	<.001	3	9
ESCA	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.057	+0.035	<.001	.001	3	8
KIRP	Regulation of cell cycle G2/M phase transition →	+0.055	+0.010	<.001	<.001	3	8
STAD	Positive regulation of chromosome organization →	+0.059	+0.025	<.001	<.001	3	8
STAD	Regulation of chromosome organization →	+0.063	+0.030	<.001	<.001	3	8
ESCA	DNA-templated DNA replication →	+0.061	+0.028	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,770 associations by consensus.

Regulation of double-strand break repair by PAICSP6 expression — STAD

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