PAICSP6

Across TCGA pan-cancer cohorts, PAICSP6 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PAICSP6 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher PAICSP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PAICSP6 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUSC show a favorable association.

PAAD, LIHC, and KIRC are the cancer types where PAICSP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.117	0.640	.007	78	view →
LIHC	OS	Tertile	All	0.217	0.712	<.001	45	view →
KIRC	OS	Tertile	All	0.489	0.646	.010	27	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	27	view →
BRCA	DFS	Tertile	All	0.900	0.503	.019	24	view →
THYM	DFS	Tertile	II,III,IV	0.083	0.900	<.001	18	view →
THCA	DFS	Tertile	All	0.783	0.937	.009	18	view →
UCEC	OS	Tertile	II,III,IV	0.297	0.543	.046	18	view →
ACC	DFS	Tertile	II,III,IV	0.195	0.659	.001	12	view →
GBM	DFS	Tertile	All	0.165	0.272	.035	9	view →
HNSC	OS	Tertile	II,III,IV	0.425	0.724	.025	6	view →
LUSC	OS	Tertile	All	0.841	0.646	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PAICSP6–PAAD (OS)

Open the PAAD breakdown →