PAGE5

Across TCGA patient cohorts, PAGE5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,438 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PAGE5-associated GO terms across cancer lineages are Anaphase-promoting complex-dependent catabolic process, Cytoplasmic translation, and CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation. Each is linked with PAGE5 in more than 11 cancer types. Because this analysis shows association rather than direction, both PAGE5-to-partner and partner-to-PAGE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anaphase-promoting complex-dependent catabolic process grouped by PAGE5-low versus PAGE5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE5→partner) and Y-score (partner→PAGE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Anaphase-promoting complex-dependent catabolic process →	+0.038	+0.503	<.001	<.001	3	12
STAD	Cytoplasmic translation →	+0.094	+0.537	<.001	.002	3	11
TGCT	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation →	+0.044	+1.508	<.001	<.001	3	9
STAD	snRNA 3'-end processing →	+0.063	+0.647	<.001	<.001	3	9
STAD	Negative regulation of binding →	+0.058	+0.428	<.001	.007	2	10
STAD	Metaphase chromosome alignment →	+0.052	+0.461	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,438 associations by consensus.

Anaphase-promoting complex-dependent catabolic process by PAGE5 expression — STAD

Explore this box plot interactively →