PAGE5

Across TCGA patient cohorts, PAGE5 protein abundance is significantly associated with the RNA expression of many other genes, with 900 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PAGE5-associated genes across cancer lineages are AKAP8, CDC37, and CCNL1. Each is linked with PAGE5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAGE5-to-partner and partner-to-PAGE5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAGE5 versus AKAP8 in LSCC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE5→partner) and Y-score (partner→PAGE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKAP8 →	-0.255	-0.791	.006	.001	3	2
BRCA	CDC37 →	-0.366	-0.821	.006	.003	3	2
BRCA	CCNL1 →	-0.451	-1.020	.009	.001	3	2
BRCA	DAZAP1 →	-0.308	-0.840	.002	<.001	3	2
BRCA	KEAP1 →	-0.503	-0.753	.002	.001	3	2
LUAD	TOMM22 →	+0.216	+1.160	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 900 associations by consensus.

PAGE5 vs AKAP8 — LSCC

Explore this scatter interactively →