PAGE2B

Across TCGA patient cohorts, PAGE2B mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAGE2B-associated genes across cancer lineages are OR4M1, MIR4747, and MIR6766. Each is linked with PAGE2B in more than 1 cancer types. Because this analysis shows association rather than direction, both PAGE2B-to-partner and partner-to-PAGE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4M1 grouped by PAGE2B-low versus PAGE2B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE2B→partner) and Y-score (partner→PAGE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR4M1 →	+0.036	+5.513	.002	.004	3	2
UCEC	MIR4747 →	+1.046	+5.133	<.001	.008	3	1
UCEC	MIR6766 →	+0.765	+5.358	<.001	.006	3	1
SKCM	GGTLC5P →	+0.041	+5.037	.001	.009	3	1
SKCM	RNU6-859P →	+0.511	+5.513	<.001	.004	3	1
SKCM	CYP2A7P1 →	+0.057	+6.199	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

OR4M1 by PAGE2B expression — SKCM

Explore this box plot interactively →